In the movie, Octavius creates his mechanical arms to aid in his experiments, just like he did in the comics. Something goes wrong during one of Otto's experiments and he is badly wounded.In the movie, the accident occurs during an experiment funded by Oscorp, which reflects Doc Ock's origin story in the Ultimate Spider-Man canon. Only in the Ultimate Spider-Man comics he was fused to his arms during the same lab explosion that turned Norman Osborn into the Green Goblin, while in the film the accident occurs during an unrelated experiment. But Oscorp is involved in the accident in both versions of the story.The scene where Otto awakens in hospital and massacres the surrounding medical staff is taken from 'Doctor Octopus' (Ultimate Spider-Man Vol 1 #14, December 2001). In both stories, he wakes to find himself lying in a hospital bed with his eyes bandaged, initially unaware that he has been fused to his metal arms.In the comic, he had been in a coma for several months before awakening, while in the movie he wakes not long after being admitted. In both stories, his metal arms slaughter the surrounding medical personnel with ruthless efficiency. The image of Otto roaming the city barefoot and shirtless is evocative of the Ultimate Spider-Man comics.After leaving the hospital, he steps into a road and is almost hit by a car. Fortunately, his new arms grant him the strength to lift the vehicle into the air. A similar scene occurred in 'Live' (Ultimate Spider-Man Vol 1 #20, June 2002).Octavius makes his way to the waterfront where he establishes his new hideout in a dilapidated warehouse. Doc Ock has had several similar hideouts in the comics, including one from 'Enter: Doctor Octopus' (Amazing Spider-Man Vol 1 #53, October 1967). The cover of this issue is included in the Spider-Man 2 DVD comic, making it likely it was a deliberate reference.

Film

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