Dr Hostetler asserts that the strongest analgesic available at the time (January 1901) is laudanum, or tincture of opium. This is untrue. Both morphine, isolated in 1803 and commercially available from Merck from 1827 on, and heroin, isolated in 1874 and commercially available from Bayer from 1895 on, would give far better pain management. Those substances would be administered intravenously, however, and laudanum had the advantage of being administered orally.
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